Affiliated Research Centers
ANCHA BARANOVA, Associate Professor. Systems biology and functional genomics of chronic human diseases including cancer, diabetes, obesity, liver disorders, computational biology and pathway analysis.
CHARLES BAILEY, Distinguished Professor. Biodefense, Biology and ecology of vector-borne infectious diseases.
VIKAS CHANDHOKE, Professor. Translational research of Liver Diseases and Metabolic Syndrome.
KARL FRYXELL, Associate Professor. Molecular evolution, computational biology and genetic pathways, functional genomics of the nervous system including cognition and nicotine addiction.
RAMIN HAKAMI, Assistant Professor. Discovery of critical host responses to infection caused by bacterial and viral pathogens and functional characterization of the identified pathways.
SALEET JAFRI, Professor. Uses computational modeling to study the molecular and cellular basis of disease. Research interests include mitochondrial physiology, cardiac physiology and disease, muscle and muscle pathologies, and t-lymphocyte signaling.
FATAH KASHANCHI, Professor. Gene Expression, Genomics and Proteomics of HIV-1 and HTLV-1 infected cells.
KYLENE KEHN-HALL, Associate Professor. Research interests are currently focused on Rift Valley fever virus (RVFV) and encephalitic alphaviruses [Venezuelan, Eastern and Western Equine Encephalitis Viruses (VEEV, EEEV, and WEEV)]. Her laboratory is focused on 1) identifying critical host factors that are necessary for viral replication, 2) evaluating small molecule inhibitors that target essential host-based events for their therapeutic potential, and, 3) developing novel diagnostic tools to enable the early detection of viral infections.
DMITRI KLIMOV, Associate Professor. Recent research uses computer simulations to investigate the assembly of peptides into ordered nanostructures, such as amyloid fibrils. Research has implications for neurodegenerative diseases, including Alzheimer's disease.
LANCE LIOTTA, Professor. Cancer research to include the process of tumor invasion and metastasis at the molecular level; technologies used to make broad discoveries in genomics, functional genomics and tissue proteomics.
ALESSANDRA LUCHINI, Assistant Professor. Studies hydrogel nanoparticles and their application in proteomics translational research. Hydrogel nanoparticles are polymeric macromolecules, functionalized with high affinity chemical baits, that mixed with biological fluids such as urine and blood can reveal the presence of otherwise invisible biomarkers. Hydrogel nanoparticles are being applied to the measurement of biomarkers for infectious diseases such as Lyme disease and tuberculosis, sweat biomarkers for schizophrenia, cancer biomarkers, and antidoping research.
AARTHI NARAYANAN-IYER, Assistant Professor. Pathogen interactions involving Bunyaviruses, Alphaviruses and Human retroviruses; Roles of extracellular vesicles intercellular communication.
EMANUEL (CHIP) PETRICOIN III, Professor. Implementation of proteomics, nanotechnology, and genomics research in cancer, metabolic syndrome, cardiopulmonary diseases, and neurodegenerative and liver diseases.
SERGUEI POPOV, Associate Professor. Mechanisms of microbial pathogenicity; microbe-host interaction during infection.
DON SETO, Professor. Viral genomics and bioinformatics. Adenoviruses are used as a model system to apply genomics and bioinformatics approaches for understanding viruses, particularly pathogens, and for changing paradigms.
JEFF SOLKA, Adjunct Assistant Professor. Statistical pattern recognition and data mining. Particularly interested in dimensionality reduction and text data mining.
IOSIF VAISMAN, Acting Director. Professor. Developing computational methods for protein structure and function analysis. Main activity areas include computational geometry or protein structure and protein structure-function relationships.
MONIQUE VAN HOEK, Associate Professor. Aerosol delivery of therapeutics using nano-aerosols. Development of novel antimicrobial and antibiofilm agents, including antimicrobial peptides. Novel vaccine development for Francisella tularensis. Host-pathogen interactions of Francisellaand other human pathogens, with a focus on the lungs.
YUNTAO WU, Professor. HIV-1 infection, resting CD4 T cells and macrophages; Role of cell signaling in HIV-1 infection and pathogenesis; HIV-1 preintegration transcription; Lentiviral vector development for targeting HIV reservoirs.
JIM WILLETT, Professor. Employs the nematodeCaenorhabditis elegansas a model system to study the molecular mechanisms driving physiologic state changes. Metabolic profiling allows detection of those metabolites and sets of metabolites that show marked, reproducible alterations as a result of such specific state changes. Recording biochemical pathway responses to physiologic state modifiers may reveal the molecular mechanisms responsible for these changes.